We envision a radically new technology for in-vivo bioresorbable sensing of analytes of clinical interest (e.g., drugs, biomarkers) where optical devices, power and light sources, synthetic receptors - made out of materials that completely dissolve with biologically benign byproducts in biofluids - will be developed and integrated together into an optoelectronic sensing system. The system is designed to be implanted in the body at a specific site of clinical relevance (i.e., site of tumor removal, under skin for melanoma, inner head for cranial trauma) during the primary surgery the patient will undergo, so as to monitor in-vivo, in-situ, and in real-time the concentration of the target analyte until needed, then the system will be fully and safely resorbed on-demand, upon an external trigger    

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